How to make drugs safer and combat aging

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My guest this week is Dr. Garret Fitzgerald, the Director of the Institute for Translational Medicine and Therapeutics at the University of Pennsylvania. We discuss his current work at Calico, a Google-backed company that aims to combat aging, including Garret's fascination with circadian rhythms. He also explains his key role in revealing the dangerous side effects of selective inhibitors of COX-2, leading to removing Vioxx from the market in 2004 and a black box warning on its competitor Celebrex.